A selective GHRP used for cleaner growth hormone pulses. Calculate your dose and learn how timing changes the result.
Pre-filled with typical ipamorelin values. Adjust to match your vial and protocol.
Ipamorelin is a selective growth hormone releasing peptide (GHRP) that stimulates the pituitary gland to release growth hormone through the ghrelin receptor pathway. Unlike older GHRPs such as GHRP-6 and GHRP-2, ipamorelin is highly selective and does not significantly increase cortisol, prolactin, or cause intense hunger spikes.
This selectivity makes ipamorelin the cleanest GHRP available, producing a strong GH pulse with minimal side effects. It is most commonly used in combination with CJC-1295 (no DAC / Mod GRF 1-29) for synergistic growth hormone optimization. The combination is widely considered the gold standard for peptide-based GH therapy.
Below are common dosing protocols for ipamorelin based on available research and community experience:
| Protocol | Dose | Notes |
|---|---|---|
| Standard Dose | 200-300 mcg | Per injection, 1-3x daily |
| With CJC-1295 Stack | 100-200 mcg each | Both peptides per injection, 2-3x daily |
| Pre-bed protocol | 200 mcg | Most important dose; 30 min before sleep, fasted |
| Typical Cycle | 8-12 weeks on, 4 weeks off | Prevents receptor desensitization |
Ready to calculate? Use the calculator above or our full calculator with syringe visualization.
Ipamorelin comes as a lyophilized (freeze-dried) powder that must be reconstituted with bacteriostatic water before use. The process is standard for all peptides:
For a detailed step-by-step guide with visuals, see our complete peptide reconstitution guide.
Understanding potential side effects helps you use ipamorelin more safely. Most side effects are dose-dependent and may improve over time.
Before reconstitution: Store lyophilized (powder) ipamorelin in a cool, dry place away from direct sunlight. Refrigeration is ideal for long-term storage of unreconstituted peptides.
After reconstitution: Store the reconstituted vial upright in a refrigerator at 36-46°F (2-8°C). Do not freeze. The solution typically remains stable for 4-6 weeks. Always swab the vial stopper with an alcohol pad before each use.
Growth hormone release is highly dependent on timing and metabolic state. For maximum GH pulse from ipamorelin:
The pre-bed fasted dose alone accounts for a large portion of the total daily GH benefit, making it the highest-priority injection if you can only dose once daily.
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